May 1, 2018

Glycanostics PCa DX kit showed 95+% accuracy on the pre-clinical validation

In April 2018  the technology validation was successfully completed indicating a great potential of Glycanostics innovative products for prostate cancer (PCa) diagnostics. The test showed 95+% accuracy (100% assay sensitivity and 94% assay specificity), which is much more accurate than the most commonly used PSA test (83% assay sensitivity and 39% assay specificity) and PCA3 benchmarks. That literally means that Glycanostics PCa DX kit can correctly identify 100% PCa patients and 94% of healthy men which makes a real revolution in prostate cancer diagnostics!

Using this innovative approach only 6% of healthy men will be sent to unnecessary biopsies, while with standard PSA this number is over 60%. In such a way Glycanostics PCa DX kit will help to avoid thousands of unnecessary biopsies which bring patients emotional distress, significant financial expenses and possible health complications.

 At the same time, Glycanostics innovative product can be also used as a second opinion test after the biopsy was performed. In fact, only 26% of biopsies confirm PCa, other 74% require further surveillance and/or re-biopsy. Another biopsy problem is that 20- 30% of PCa patients are diagnosed false-negative. Thus using Glycanostics PCa DX kit as a second opinion test after performed biopsy can decrease mortality, increase the efficiency of treatment and avoid unnecessary sufferings as well as financial loads for patients.

 “Our next steps are optimization of the assay performance and pre-clinical and retrospective validation study with 450 serum samples. That will speed up the process of commercialization of the clinical test and bring it to the market.” 

comments professor Jan Tkac, co-founder and executive manager of Glycanostics Ltd.

Other News

June 22, 2021

Glycanostics meet the President of the EC Mrs. Ursula von der Leyen

On Monday, June, 21st our CEO Eva Kovacova (on the right) together with CSO Jan Tkac (on the left) had a great honour to introduce the company Glycanostics to the President of the EC Mrs. Ursula von der Leyen, our Prime Minister Mr. Eduard Heger and Vice-President of the EC Mr. Maros Sefcovic. As one out of seven selected innovative companies, we presented our highly accurate, non-invasive, and early-stage cancer diagnostics that can help save the lives of millions of people worldwide.

October 18, 2019

A highly-prestigious award for a Glycanostics co-founder

ESET launched a prestigious ESET Science Award for exceptional scientists

October 3, 2019

International Patent Application No. PCT/EP2019/057386

Means and methods for glycoprofiling of a protein

August 31, 2019

Glycanostics succesfully finished Horizon 2020 SME Instrument 1 Grant

Glycanostics successfully finished the first phase of SME Instrument

December 10, 2018

Glycanostics Wins Horizon 2020 Grant

After receiving the prestigious “Seal of Excellence” on October 23, the next submission to the Horizon 2020 Programme, won a € 50 000 grant.

October 27, 2018

Glycanostics Receives the Prestigious Horizon 2020 “Seal of Excellence”

This project received the highest scores for its proposal in the extremely competitive evaluation process.

October 24, 2018

Glycanostics Wins TOP-6 Best Startups in Central Europe

Glycanostics was chosen as a finalist in the Grand Finale with five other remarkable startups.

August 14, 2018

Glycanostics Applies for Innovation-Securing Patent

The application covering Glycanostics' diagnostic method is currently filed in two patent offices in Europe and Luxemburg.

July 27, 2018

Glycanostics wins the European Research Council Grant

Glycanoctics innovations are again supported and highly ranked by leading industry experts. This time the company won the European Research Council (ERC) Proof of Concept Grant.

June 14, 2018

Glycanostics Takes 3rd Place in Vodafone’s Idea of The Year Competition

The competition's objectives are to actively support innovative projects with high market potential

November 30, 2017

Jan Tkac and Tomas Bertok – Scientists of the year award winners - establish Glycanostics to bring their revolutionary innovation to cancer diagnostics market

Glycanostics is an innovative start-up company established in 2017 to bring its revolutionary cancer diagnostics products to the US and EU markets.